Teratogenic Effects: Pregnancy Category C. Grepafloxacin had neither embryolethal nor teratogenic effects in rats when administered orally or intravenously. There was no compound-related effect on maintenance of pregnancy, parturition , implantation of females, ovulation , nursing, or on viability, body weight, or morphology of fetuses. However, a decrease in placental weight and in the number of ossified saccrococcygeal vertebrae were observed in rats at times the recommended maximum daily human dose based on mg/m 2 (15 times the recommended maximum daily human dose on a mg/kg basis); this was associated with maternal toxicity (decreased body weight and food consumption). No effect was noted at 420 mg/m 2 per day (equivalent to the human dose).
Our client list includes the “big three” automakers, as well as their suppliers. Other customers include Whirlpool, Arctic Cat, and MTD: a leading maker of outdoor power equipment. From makers of off-road vehicles to appliances and more, numerous industries have experienced the quality, reliability, and innovation of our new and rebuilt machines.
West Michigan Spline is your “best in class” machine tool manufacturer. Every day, our employees are dedicated to producing high-quality machines, creating new and innovative designs, and delivering unmatched customer service.